1H-1,2,3-三氮唑合成路线

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JANSSEN PHARMACEUTICA NV; LETAVIC, Michael; RUDOLPH, Dale, A.; SAVALL, Brad, M.; SHIREMAN, Brock, T.; SWANSON, Devin
Patent: WO2012/145581 A1, 2012 ;
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WO 2012/145581 A1

52548-14-82-碘-5-甲基苯甲酸+

288-36-81H-1,2,3-三氮唑

956317-36-52-(2H-1,2,3-噻唑-2-基)-5-甲基苯甲酸

参考文献

MERCK SHARP andamp; DOHME CORP.; COX, Christopher, D.; FLORES, Broc; SCHREIER, John, D.
Patent: WO2010/48016 A1, 2010 ;
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WO 2010/048016 A1

288-36-81H-1,2,3-三氮唑+

52548-14-82-碘-5-甲基苯甲酸

956317-36-52-(2H-1,2,3-噻唑-2-基)-5-甲基苯甲酸

参考文献

Cox, Christopher D.; Breslin, Michael J.; Whitman, David B.; Schreier, John D.; McGaughey, Georgia B.; Bogusky, Michael J.; Roecker, Anthony J.; Mercer, Swati P.; Bednar, Rodney A.; Lemaire, Wei; Bruno, Joseph G.; Reiss, Duane R.; Harrell, C. Meacham; Murphy, Kathy L.; Garson, Susan L.; Doran, Scott M.; Prueksaritanont, Thomayant; Anderson, Wayne B.; Tang, Cuyue; Roller, Shane; Cabalu, Tamara D.; Cui, Donghui; Hartman, George D.; Young, Steven D.; Koblan, Ken S.; Winrow, Christopher J.; Renger, John J.; Coleman, Paul J.
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288-36-81H-1,2,3-三氮唑+

6967-82-42-溴-5-甲基苯甲酸

956317-36-52-(2H-1,2,3-噻唑-2-基)-5-甲基苯甲酸

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EOLAS THERAPEUTICS, INC.; KAMENECKA, Theodore; JIANG, Rong; SONG, Xinyi
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288-36-81H-1,2,3-三氮唑+

17201-43-3对氰基溴化苄

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Doiron, Jeremie; Soultan, Al Haliffa; Richard, Ryan; Toure, Mamadou Mansour; Picot, Nadia; Richard, Remi; Cuperlovic-Culf, Miroslava; Robichaud, Gilles A.; Touaibia, Mohamed
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 9 p. 4010 - 4024

288-36-81H-1,2,3-三氮唑+

350-46-9对氟硝基苯

1204-91-7

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Kitazaki, Tomoyuki; Ichikawa, Takashi; Tasaka, Akihiro; Hosono, Hiroshi; Matsushita, Yoshihiro; Hayashi, Ryogo; Okonogi, Kenji; Itoh, Katsumi
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 12 p. 1935 - 1946

288-36-81H-1,2,3-三氮唑+

350-46-9对氟硝基苯

1204-91-7

参考文献

Jia, Zhaozhong J.; Wu, Yanhong; Huang, Wenrong; Zhang, Penglie; Clizbe, Lane A.; Goldman, Erick A.; Sinha, Uma; Arfsten, Ann E.; Edwards, Susan T.; Alphonso, Merlyn; Hutchaleelaha, Athiwat; Scarborough, Robert M.; Zhu, Bing-Yan
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 5 p. 1221 - 1227

288-36-81H-1,2,3-三氮唑+

126144-60-3

52417-09-1+

176755-83-2

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Marcusson, Eric G.; Dobie, Kenneth W.; Freier, Susan M.
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288-36-81H-1,2,3-三氮唑+

40615-39-2保护胸苷+

10025-87-3三氯氧磷

176755-83-2

参考文献

Freier, Susan M.; Dobie, Kenneth W.; Koller, Erich
Patent: US2003/225019 A1, 2003 ;
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288-36-81H-1,2,3-三氮唑+

350-46-9对氟硝基苯

52708-34-6+

16279-88-2

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MERCK CANADA INC.; BOYD, Michael John; CHIASSON, Jean-François; CRANE, Sheldon; GIROUX, André
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