Block, Michael Howard; Donald, Craig Samuel; Brittain, David Robert; Foote, Kevin Michael
Patent: US2003/225097 A1, 2003 ;
Location in patent: Page 51 ;
de Knaep; Vandendriessche; Daemen; Dingenen; Laenen; Nijs; Pauwels; van den Heuvel; van der Eycken; Vanierschot; van Laar; Verstappen; Willemsens
Organic Process Research and Development, 2000 , vol. 4, # 3 p. 162 - 166
1: With triethylamine; trichlorophosphate in acetonitrile
T=-20 - 0°C; 2 h;
2: With water in acetonitrile
T=10°C;
3: With ammonia in 1,4-dioxane; water
参考文献
Isis Pharmaceuticals Inc.
Patent: US2003/232773 A1, 2003 ;
Location in patent: Page 17 ;
