lithium aluminium tetrahydride in tetrahydrofuran T=-78°C; 12 h;

1: ethyl vinyl ether With tert.-butyl lithium in tetrahydrofuran; pentane T=-78 - -5°C; 1 h; 2: (E)-2-methyl-1-morpholin-4-yl-3-phenylprop-2-en-1-one in tetrahydrofuran; pentane T=-78°C; 1 h;

1.1: tert-butyllithium / pentane; tetrahydrofuran / 1 h / -78 - -5 °C 1.2: pentane; tetrahydrofuran / 1 h / -78 °C 2.1: 100 percent / HCl / acetone; H2O / 72 h / 20 °C View Scheme