3-(4-甲氧苯基)-3-氧代丙酸乙酯合成路线 （共 58 条）
反应条件
diethyl ether; ammonia; sodium amide Erwaermen des Reaktionsgemisches mit Kohlensaeure-diaethylester in Aether;
参考文献
Nippon Shinyaku Company Limited
Patent: US5342845 A1, 1994 ;
反应条件
1: 85 percent / K3<Fe(CN)6>-K2CO3 / (DHQ2-TP)-OsO4 / 2-methyl-propan-2-ol; H2O 2: 98 percent / SOCl2, pyridine / 2 h / 0 °C 3: 15 percent / toluene / 12 h / Heating View Scheme
参考文献
Lohray; Jayachandran; Bhushan; Nandanan; Ravindranathan
Journal of Organic Chemistry, 1995 , vol. 60, # 18 p. 5983 - 5985
反应条件
1: ethyl methyl carbonate With sodium hydride T=20°C; Inert atmosphere; 2: 1-(4-methoxyphenyl)ethanone 4 h; Inert atmosphereReflux;
参考文献
Balamurugan, Rengarajan; Manojveer, Seetharaman
Chemical Communications, 2011 , vol. 47, # 39 p. 11143 - 11145
反应条件
zinc in tetrahydrofuran 1) 30 deg C, 2 h, 2) reflux, 18 h;
参考文献
Kashima, Choji; Huang, Xin Cheng; Harada, Yukari; Hosomi, Akira
Journal of Organic Chemistry, 1993 , vol. 58, # 3 p. 793 - 794
反应条件
samarium; iodine in tetrahydrofuran 1.5 h; Heating;
参考文献
Zou, Xuefei; Jia, Xiaofei; Wang, Xiaoxia; Xie, Guanqun
Synthetic Communications, 2007 , vol. 37, # 10 p. 1617 - 1625
反应条件
1.1: LDA / tetrahydrofuran / 2 h / -78 °C 1.2: 75 percent / tetrahydrofuran / 2 h / -78 - 20 °C 2.1: 83 percent / aq. H2O2 / tetrahydrofuran / 3 h / 20 - 50 °C View Scheme
参考文献
Chen, Shufeng; Yuan, Fang; Zhao, Haiying; Li, Baoguo
RSC Advances, 2013 , vol. 3, # 31 p. 12616 - 12620
反应条件
sodium ethanolate in ethanol Heating;
参考文献
Potts, Kevin T.; Cipullo, Michael J.; Ralli, Philip; Theodoridis, George
Journal of Organic Chemistry, 1982 , vol. 47, # 16 p. 3027 - 3038
反应条件
1: polystyrene-supported α-seleno acetate, loading 1.64 mmol/g (COOH) With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 0.5 h; 2: 4-methoxy-benzaldehyde in tetrahydrofuran T=-78 - 20°C; 2.5 h; 3: With dihydrogen peroxide in tetrahydrofuran T=20°C;
参考文献
Qian, Hao; Huang, Xian
Synlett, 2006 , # 10 p. 1547 - 1548
反应条件
ethanol; sodium T=20°C; Claisen Condensation; 8 h;
参考文献
Chen, Qianqian; Tian, Wei; Han, Guangqian; Qi, Jingjing; Zheng, Canhui; Zhou, Youjun; Ding, Lili; Zhao, Juntao; Zhu, Ju; Lv, Jiaguo; Sheng, Chunquan
European Journal of Medicinal Chemistry, 2013 , vol. 59, p. 176 - 182
参考文献
Cragg, John E.; Herbert, Richard B.; Jackson, Frederick B.; Moody, Christopher J.; Nicolson, Ian T.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 10 p. 2477 - 2486
