5-甲氧基-2-甲基-3-吲哚乙酸合成路线 （共 45 条）
反应条件
sodium hydroxide in acetonitrile T=25°C; Rate constant;
参考文献
Cipiciani; Ebert; Linda; Rubessa; Savelli
Journal of Pharmaceutical Sciences, 1983 , vol. 72, # 9 p. 1075 - 1076
反应条件
sodium hydroxide in acetonitrile T=25°C; Rate constant;
参考文献
Cipiciani; Ebert; Linda; Rubessa; Savelli
Journal of Pharmaceutical Sciences, 1983 , vol. 72, # 9 p. 1075 - 1076
反应条件
10-[2-(dimethylamino)propyl]phenothiazine in water T=20°C; pH 3.0; Rate constantEquilibrium constant;
参考文献
Jovanovic, Slobodan V.; Steenken, Steen
Journal of Physical Chemistry, 1992 , vol. 96, # 16 p. 6674 - 6679
反应条件
hydrogenchloride; N-benzyl-trimethylammonium hydroxide 1.) THF, reflux, 10 h, 2.) aq. ethanol, room temp., 1 h; Multistep reaction;
参考文献
Garuti; Giovanninetti; Bova; Chiarini
Archiv der Pharmazie, 1988 , vol. 321, # 7 p. 377 - 383
反应条件
sodium hydroxide; sodium lauryl sulfate T=25°C; equilibrium constant for substrate binding; further reagent: hexadecyltrimethylammonium bromide; Rate constant;
参考文献
Cipiciani; Ebert; Germani; Linda; Lovrecich; Rubessa; Savelli
Journal of Pharmaceutical Sciences, 1985 , vol. 74, # 11 p. 1184 - 1187
反应条件
in water T=30°C; Kinetics; Further Variations:pH-valuesTemperatures;
参考文献
Zouvelekis, Dimitris; Yannakopoulou, Konstantina; Mavridis, Irene M; Antoniadou-Vyza, Ekaterini
Carbohydrate research, 2002 , vol. 337, # 15 p. 1387 - 1395
反应条件
Fischer indole synthesis;
参考文献
Iwahashi, Maki; Shimabukuro, Atsushi; Onoda, Takahiro; Matsunaga, Yoko; Okada, Yutaka; Matsumoto, Ryoji; Nambu, Fumio; Nakai, Hisao; Toda, Masaaki
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 15 p. 4574 - 4588
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; potassium hexamethylsilazane 1.) THF; Multistep reaction;
参考文献
Gallant, Michel; Dufresne, Claude; Gareau, Yves; Guay, Daniel; Leblanc, Yves; Prasit, Petpiboon; Rochette, Chantal; Sawyer, Nicole; Slipetz, Deborah M.; Tremblay, Nathalie; Metters, Kathleen M.; Labelle, Marc
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2263 - 2268
反应条件
1: DCC / tetrahydrofuran 2: 1.) KHMDS, HMPA / 1.) THF View Scheme
参考文献
Gallant, Michel; Dufresne, Claude; Gareau, Yves; Guay, Daniel; Leblanc, Yves; Prasit, Petpiboon; Rochette, Chantal; Sawyer, Nicole; Slipetz, Deborah M.; Tremblay, Nathalie; Metters, Kathleen M.; Labelle, Marc
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2263 - 2268
反应条件
1: 59 percent / 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 1-hydroxybenzotriazole; ethyldiisopropylamine / ammonium chloride / dimethylformamide / 5 h / 20 °C 2: 73 percent / LiAlH4 / tetrahydrofuran / 60 h / 20 °C View Scheme
参考文献
Shaw
Journal of the American Chemical Society, 1955 , vol. 77, p. 4319,4320
Journal of the American Chemical Society, 1956 , vol. 78, p. 6419
