3-氨基-2-苯乙炔基吡啶合成路线 （共 6 条）
反应条件
copper(l) iodide; triethylamine; triphenylphosphine; palladium dichloride T=80°C; Sonogashira cross-coupling; 20 h;
参考文献
Koradin, Christopher; Dohle, Wolfgang; Rodriguez, Alain L.; Schmid, Bertram; Knochel, Paul
Tetrahedron, 2003 , vol. 59, # 9 p. 1571 - 1587
反应条件
ammonium chloride; tin(ll) chloride in ethanol T=60°C; 24 h;
参考文献
Sun, Li-Ping; Wang, Jin-Xin
Synthetic Communications, 2007 , vol. 37, # 13 p. 2187 - 2193
反应条件
1: 84 percent / triethylamine; CuI / Pd(PPh3)4 / acetonitrile / 2 h / 20 °C 2: 80 percent / tin(II) chloride dihydrate; NH4Cl / ethanol / 24 h / 60 °C View Scheme
参考文献
Sun, Li-Ping; Wang, Jin-Xin
Synthetic Communications, 2007 , vol. 37, # 13 p. 2187 - 2193
反应条件
1: 84 percent / triethylamine; CuI / Pd(PPh3)4 / acetonitrile / 2 h / 20 °C 2: 80 percent / tin(II) chloride dihydrate; NH4Cl / ethanol / 24 h / 60 °C View Scheme
参考文献
Sun, Li-Ping; Wang, Jin-Xin
Synthetic Communications, 2007 , vol. 37, # 13 p. 2187 - 2193
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine T=50°C; Sonogashira Cross-Coupling; Inert atmosphere;
参考文献
Liu, Bifu; Gao, Hanling; Yu, Yue; Wu, Wanqing; Jiang, Huanfeng
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10319 - 10328
反应条件
potassium tert-butylate in 1-methyl-pyrrolidin-2-one T=20°C; 24 h;
参考文献
Sun, Li-Ping; Wang, Jin-Xin
Synthetic Communications, 2007 , vol. 37, # 13 p. 2187 - 2193
