Boc-L-丙氨酸甲基酯合成路线 （共 43 条）
反应条件
triethylamine in dichloromethane T=0°C;
参考文献
Kobayashi, Kazuya; Narumi, Tetsuo; Oishi, Shinya; Ohno, Hiroaki; Fujii, Nobutaka
Journal of Organic Chemistry, 2009 , vol. 74, # 12 p. 4626 - 4629
反应条件
sodium hydrogencarbonate; sodium chloride in chloroform; water 3 h; Heating;
参考文献
Mruk, Ralf; Zentel, Rudolf
Macromolecules, 2002 , vol. 35, # 1 p. 185 - 192
反应条件
hydrogen; palladium dihydroxide in methanol; ethyl acetate P=3620.04 Torr; 120 h;
参考文献
Merino, Pedro; Castillo, Elena; Franco, Santiago; Merchan, Francisco L.; Tejero, Tomas
Journal of Organic Chemistry, 1998 , vol. 63, # 7 p. 2371 - 2374
反应条件
Rh(1+)*2CH4O*C4H12B(1-)*C34H40O2P2; hydrogen in methanol T=22°C; P=750.075 Torr; 0.0666667 h; Inert atmosphere; enantioselective reaction;
参考文献
Mohar, Barbara; Stephan, Michel
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 2-3 p. 594 - 600
反应条件
PMHS; palladium dihydroxide in ethanol T=20°C; 5 h;
参考文献
Chandrasekhar; Babu, B. Nagendra; Reddy, Ch. Raji
Tetrahedron Letters, 2003 , vol. 44, # 10 p. 2057 - 2059
反应条件
4-methyl-morpholine; 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride
参考文献
TOKUYAMA CORPORATION
Patent: EP1178043 A1, 2002 ;
Location in patent: Page 31, 32 ;
反应条件
sodium carbonate in N,N-dimethyl-formamide T=20°C; Inert atmosphere;
参考文献
Xu, Zhigang; DiCesare, John C.; Baures, Paul W.
Journal of Combinatorial Chemistry, 2010 , vol. 12, # 2 p. 248 - 254
参考文献
Stichting Katholieke Universiteit
Patent: US4820712 A1, 1989 ;
反应条件
in methanol; diethyl ether; benzene 0.5 h;
参考文献
Singh, Erinprit K.; Ramsey, Deborah M.; McAlpine, Shelli R.
Organic Letters, 2012 , vol. 14, # 5 p. 1198 - 1201
反应条件
1: N-[(1,1-dimethylethoxy)carbonyl]-3-iodo-L-alanine methyl ester With chloro-trimethyl-silane; ethylene dibromide; zinc in tetrahydrofuran T=45°C; 1.45 h; 2: Sphenyl N-benzyloxycarbonylaminoethanothioate With tris-(o-tolyl)phosphine; tris(dibenzylideneacetone)dipalladium (0) in tetrahydrofuran T=45°C; 4.5 h;
参考文献
Estiarte, M.Angels; Diez, Anna; Rubiralta, Mario; Jackson, Richard F.W
Tetrahedron, 2001 , vol. 57, # 1 p. 157 - 161
