5-氯-2-碘-苯甲酸甲酯合成路线 （共 3 条）
反应条件
sodium hydrogencarbonate in N,N-dimethyl-formamide
T=20°C; 24 h;
参考文献
CONSTELLATION PHARMACEUTICALS, INC.; ALBRECHT, Brian, K.; HEWITT, Miichael, Charles; GEHLING, Victor, S.; VASWANI, Rishi, G.
Patent: WO2013/184876 A1, 2013 ;
Location in patent: Paragraph 00144; 00151; 00152 ;
反应条件
anhydrous sodium hydrogen carbonate; Ki; sulfuric acid; sodium nitrite in water; acetic acid
参考文献
Tokunaga, Teruhisa; Hume, William Ewan; Kitoh, Makoto; Nagata, Ryu
Patent: US2003/181496 A1, 2003 ;
参考文献
Thorarensen, Atli; Wakefield, Brian D.; Romero, Donna L.; Marotti, Keith R.; Sweeney, Michael T.; Zurenko, Gary E.; Rohrer, Douglas C.; Han, Fusen; Bryant Jr., Garold L.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 10 p. 2823 - 2827
