1: (S)-2-amino-3-methoxypropanoic acid hydrochloride With sodium hydroxide in 1,4-dioxane; water T=20°C; 0.5 h; 2: (9H-Fluoren-9-yl)-methyl chloroformate in 1,4-dioxane; water T=0 - 20°C; 4 h;
参考文献
Proteolix, Inc.
Patent: US2007/105786 A1, 2007 ;
Location in patent: Page/Page column 33; 34 ;
1: copper(II) complex of Nδ-tert-butoxycarbonyl-L-ornithine With 8-hydroxy-quinoline; sodium carbonate in acetone 1 h; 2: (9H-Fluoren-9-yl)-methyl chloroformate With 1-hydroxy-pyrrolidine-2,5-dione in water T=-5°C; 0.5 h;
参考文献
Wiejak; Masiukiewicz; Rzeszotarska
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 9 p. 1189 - 1191
