(NH4)2CO3 in water T=20°C; 72 h; Cooling with ice;

1: 1-Phenylmethyl-piperidin-4-one; (NH4)2CO3 in methanol; water Cooling with ice; 2: potassium cyanide With water in methanol T=20°C; 72 h; Cooling with ice;

(NH4)2CO3 in methanol; water T=130°C; 0.133333 h; Sealed vialMicrowave irradiation;

in ethanol; water T=60°C; 12 h;

(NH4)2CO3 in ethanol; water T=60°C; Product distribution / selectivity;

in ethanol T=60°C; 48 h;

1: With water; sodium hydroxide T=80 - 108°C; Industry scale; 2: With hydrogenchloride in water T=10 - 23°C; pH=7 - 8; Industry scale;

1.1: sodium hydroxide; water / 80 - 108 °C / Industry scale 1.2: 10 - 23 °C / pH 7 - 8 / Industry scale 2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 19 - 29 °C / Cooling 2.2: 8 - 56 °C 3.1: dichloromethane; water / 0.58 h / Cooling with ice 4.1: potassium tert-butylate / 1,1-dimethylpropan-1-ol / 0.5 h / 20 °C / Inert atmosphere 5.1: hydrogen / palladium 10 on activated carbon / tetrahydrofuran / Inert atmosphere View Scheme