2-溴噻吩并[3,2-c]吡啶-4(5H)-酮合成路线 （共 5 条）
反应条件
1: With diphenylether in dichloromethane T=150°C; 2: T=220°C; 1 h;
参考文献
WO2004/828 A1, ;
WO 2004/000828 A1
反应条件
1: piperidine / pyridine / Reflux 2: diphenyl phosphoryl azide; triethylamine / toluene / 20 °C 3: benzophenone / 250 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 16 p. 4823 - 4827
反应条件
1: diphenyl phosphoryl azide; triethylamine / toluene / 20 °C 2: benzophenone / 250 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 16 p. 4823 - 4827
反应条件
1: With trichlorophosphate T=0°C; 2: T=135°C; 2.5 h;
参考文献
WO2004/828 A1, ;
WO 2004/000828 A1
反应条件
potassium carbonate in DMF (N,N-dimethyl-formamide); water
T=85°C; 2.16667 h;
参考文献
Tularik Inc.
Patent: US2004/97485 A1, 2004 ;
Location in patent: Page/Page column 41 ;
US 20040097485 A1
