2-甲氧基-6-甲基苯酚合成路线 （共 40 条）
反应条件
hydrogen; acetic acid; palladium on activated charcoal in ethyl acetate 72 h;
参考文献
Singh, Udai S.; Scannell, Ralph T.; An, Haoyun; Carter, Barbara J.; Hecht, Sidney M.
Journal of the American Chemical Society, 1995 , vol. 117, # 51 p. 12691 - 12699
反应条件
hydrogen; trifluoroacetic acid; palladium on activated charcoal in acetic acid T=100°C; P=3040 Torr; 7 h;
参考文献
Weinstock; Ladd; Wilson; Brush; Yim; Gallagher Jr.; McCarthy; Silvestri; Sarau; Flaim
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2315 - 2325
反应条件
1,3-dimethyl-imidazolidin-2-one; sodium hexamethyldisilazane in tetrahydrofuran T=185°C; 12 h;
参考文献
Arai, Shigeru; Sudo, Yukinori; Nishida, Atsushi
Synlett, 2004 , # 6 p. 1104 - 1106
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C;
参考文献
Pallavicini; Fumagalli; Gobbi; Bolchi; Colleoni; Moroni; Pedretti; Rusconi; Vistoli; Valoti
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 9 p. 1025 - 1040
反应条件
trimethylsilyl iodide in chloroform 48 h; Ambient temperature;
参考文献
Zhang, Xiuguo; Fox, Brian W.; Hadfield, John A.
Synthetic Communications, 1996 , vol. 26, # 1 p. 49 - 62
反应条件
palladium 10 on activated carbon; hydrogen; acetic acid in ethyl acetate T=20°C; 72 h;
参考文献
Lee, Chia-Lin; Huang, Chi-Huan; Wang, Hui-Chun; Chuang, Da-Wei; Wu, Ming-Jung; Wang, Sheng-Yang; Hwang, Tsong-Long; Wu, Chin-Chung; Chen, Yeh-Long; Chang, Fang-Rong; Wu, Yang-Chang
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 1 p. 70 - 73
反应条件
1: 72 percent / aq. NaOH / ethanol / 24 h / 20 °C 2: 77 percent / hydrogen / Pd/C / methanol / 20 °C View Scheme
参考文献
Pallavicini; Fumagalli; Gobbi; Bolchi; Colleoni; Moroni; Pedretti; Rusconi; Vistoli; Valoti
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 9 p. 1025 - 1040
反应条件
1: 18-crown-6 ether; potassium carbonate / acetone / 5 h / Reflux 2: sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide View Scheme
参考文献
Kevwitch, Robert M.; Shanahan, Charles S.; McGrath, Dominic V.
New Journal of Chemistry, 2012 , vol. 36, # 2 p. 492 - 505
参考文献
Lian, Yiqian; Wulff, William D.
Journal of the American Chemical Society, 2005 , vol. 127, # 49 p. 17162 - 17163
反应条件
1: sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide 2: 18-crown-6 ether; potassium carbonate / acetone / 5 h / Reflux 3: sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide View Scheme
参考文献
Kevwitch, Robert M.; Shanahan, Charles S.; McGrath, Dominic V.
New Journal of Chemistry, 2012 , vol. 36, # 2 p. 492 - 505
