(9alpha,13alpha,14alpha)-3-甲氧基-吗喃-17-甲醛合成路线 （共 11 条）
反应条件
oxygen; lithium perchlorate; 9,10-anthracenedicarbonitrile in acetonitrile T=20°C; Irradiation;
参考文献
Santamaria, J.; Ouchabane, R.; Rigaudy, J.
Tetrahedron Letters, 1989 , vol. 30, # 30 p. 3977 - 3980
反应条件
1: 5 h / 150 °C 2: POCl3 / benzene / Heating 3: pyridine; tetrahydrofuran / 8 h / 0 °C 4: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme
参考文献
Kitamura, M.; Hsiao, Yi; Noyori, R.; Takaya, H.
Tetrahedron Letters, 1987 , vol. 28, # 41 p. 4829 - 4832
反应条件
1: pyridine; tetrahydrofuran / 8 h / 0 °C 2: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme
参考文献
Kitamura, M.; Hsiao, Yi; Noyori, R.; Takaya, H.
Tetrahedron Letters, 1987 , vol. 28, # 41 p. 4829 - 4832
反应条件
1: POCl3 / benzene / Heating 2: pyridine; tetrahydrofuran / 8 h / 0 °C 3: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme
参考文献
Kitamura, M.; Hsiao, Yi; Noyori, R.; Takaya, H.
Tetrahedron Letters, 1987 , vol. 28, # 41 p. 4829 - 4832
反应条件
1: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme
参考文献
Kitamura, M.; Hsiao, Yi; Noyori, R.; Takaya, H.
Tetrahedron Letters, 1987 , vol. 28, # 41 p. 4829 - 4832
反应条件
1: 5 h / 150 °C 2: POCl3 / benzene / Heating 3: pyridine; tetrahydrofuran / 8 h / 0 °C 4: H2 / Ru(OCOCF3)2<(S)-tolbinap> / methanol / 100 h / 30 °C / 76000.1 Torr View Scheme
参考文献
Kitamura, M.; Hsiao, Yi; Noyori, R.; Takaya, H.
Tetrahedron Letters, 1987 , vol. 28, # 41 p. 4829 - 4832
参考文献
Passarotti; Valenti; Grianti
Bollettino Chimico Farmaceutico, 1993 , vol. 132, # 11 p. 475 - 477
反应条件
ammonium hydroxide; formic acid Heating; Yield given;
参考文献
Newman, Amy Hauck; Bevan, Kathryn; Bowery, Norman; Tortella, Frank C.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4135 - 4142
反应条件
hydrogen bromide 5 h; Heating;
参考文献
Passarotti; Valenti; Grianti
Bollettino Chimico Farmaceutico, 1993 , vol. 132, # 11 p. 475 - 477
反应条件
1: 3.2 g / 48percent aq. HBr / 5 h / Heating 2: 1.) formic acid, 2.) 1 N methanolic NaOH / 1.) H2O, reflux, 5 h, 2.) reflux, 2 h View Scheme
参考文献
Passarotti; Valenti; Grianti
Bollettino Chimico Farmaceutico, 1993 , vol. 132, # 11 p. 475 - 477
