3-溴噻吩并[2,3-b]吡啶合成路线 （共 6 条）
反应条件
dipotassium hydrogenphosphate; bromine; sodium hydrogencarbonate; magnesium sulfate in chloroform Heating / reflux;
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/107784 A1, 2006 ;
Location in patent: Page/Page column 94 ;
WO 2006/107784 A1
反应条件
(i) nBuLi, hexane, ether, (ii) /BRN= 1737614/, EtOH; Multistep reaction;
参考文献
Klemm,L.H.; Merril,R.E.
Journal of Heterocyclic Chemistry, 1974 , vol. 11, p. 355 - 361
反应条件
(i) nBuLi, hexane, ether, (ii) /BRN= 605365/; Multistep reaction;
参考文献
Klemm,L.H.; Merril,R.E.
Journal of Heterocyclic Chemistry, 1974 , vol. 11, p. 355 - 361
反应条件
(i) nBuLi, hexane, ether, (ii) /BRN= 605439/; Multistep reaction;
参考文献
Klemm,L.H.; Merril,R.E.
Journal of Heterocyclic Chemistry, 1974 , vol. 11, p. 355 - 361
反应条件
(i) nBuLi, hexane, ether, (ii) /BRN= 385653/; Multistep reaction;
参考文献
Klemm,L.H.; Merril,R.E.
Journal of Heterocyclic Chemistry, 1974 , vol. 11, p. 355 - 361
反应条件
copper(l) chloride in N,N-dimethyl-formamide
T=130°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2006/107784 A1, 2006 ;
Location in patent: Page/Page column 103 ;
WO 2006/107784 A1
