3-[苄基(叔丁氧羰基)胺]丙酸合成路线 （共 6 条）
反应条件
1: With sodium hydroxide; water in ethanol T=70°C; 2 h; 2: With hydrogenchloride in ethanol; water T=20°C; pH=4;
参考文献
Actelion Pharmaceuticals Ltd.
Patent: US2009/62342 A1, 2009 ;
Location in patent: Page/Page column 14 ;
反应条件
dipyridinium dichromate in N,N-dimethyl-formamide T=20°C; Oxidation; 3 h;
参考文献
De Michelis; Rocheblave; Priem; Chermann; Kraus
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 6 p. 1253 - 1262
反应条件
water; sodium hydroxide in methanol T=20°C; 3 h;
参考文献
Zerovnik, Darja; Groselj, Uros; Kralj, David; Malavasic, Crt; Bezensek, Jure; Dahmann, Georg; Stare, Katarina; Meden, Anton; Stanovnik, Branko; Svete, Jurij
Synthesis, 2010 , # 19 art. no. T09210SS, p. 3363 - 3373
反应条件
1: NaBH4 / ethanol / 2 h / 0 °C 2: CH2Cl2 / 3 h / 0 °C 3: PDC / dimethylformamide / 3 h / 20 °C View Scheme
参考文献
De Michelis; Rocheblave; Priem; Chermann; Kraus
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 6 p. 1253 - 1262
反应条件
1: Na2SO4 / CH2Cl2 / 20 °C 2: NaBH4 / ethanol / 2 h / 0 °C 3: CH2Cl2 / 3 h / 0 °C 4: PDC / dimethylformamide / 3 h / 20 °C View Scheme
参考文献
De Michelis; Rocheblave; Priem; Chermann; Kraus
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 6 p. 1253 - 1262
反应条件
1: CH2Cl2 / 3 h / 0 °C 2: PDC / dimethylformamide / 3 h / 20 °C View Scheme
参考文献
De Michelis; Rocheblave; Priem; Chermann; Kraus
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 6 p. 1253 - 1262
