N-(叔丁氧羰基)-L-2-苯甘氨酸合成路线 （共 40 条）
反应条件
sodium hydroxide in 1,4-dioxane T=0 - 20°C; 2 h;
参考文献
Bodas, Mandar S.; Upadhyay, Puspesh K.; Kumar, Pradeep
Tetrahedron Letters, 2004 , vol. 45, # 5 p. 987 - 988
反应条件
hydrogenchloride; sodium hydroxide in tetrahydrofuran; water
参考文献
J. Uriach and Cia, S.A.
Patent: US5420131 A1, 1995 ;
US 5420131 A
反应条件
N,N-dioctyl-1-octylamine; water in various solvent(s) T=37°C; pH=8.0; 48 h;
参考文献
Arosio, Dario; Caligiuri, Antonio; D'Arrigo, Paola; Pedrocchi-Fantoni, Giuseppe; Rossi, Cristina; Saraceno, Caterina; Servi, Stefano; Tessaro, Davide
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 8-9 p. 1345 - 1348
反应条件
sodium hydroxide in tetrahydrofuran; water T=20°C; 4 h;
参考文献
Shang, Ruofeng; Liu, Yu; Xin, Zhijun; Guo, Wenzhu; Guo, Zhiting; Hao, Baocheng; Jianping, Liang
European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 231 - 238
反应条件
sodium hydroxide in 1,4-dioxane 24 h; Ambient temperature;
参考文献
Katritzky, Alan R.; Fali, Clara N.; Li, Jianqing; Ager, David J.; Prakash, Indra
Synthetic Communications, 1997 , vol. 27, # 9 p. 1623 - 1630
反应条件
1: (R)-binaphthol derivative / CH2Cl2 / 1 h / 20 °C 2: aq. Oxone(R); K2CO3 / CH2Cl2; acetone / 0 °C 3: DIBAH / toluene / -78 °C 4: aq. Na2CO3; NaIO4; KMnO4 / 24 h / 20 °C View Scheme
参考文献
Uraguchi, Daisuke; Terada, Masahiro
Journal of the American Chemical Society, 2004 , vol. 126, # 17 p. 5356 - 5357
反应条件
1: aq. Oxone(R); K2CO3 / CH2Cl2; acetone / 0 °C 2: DIBAH / toluene / -78 °C 3: aq. Na2CO3; NaIO4; KMnO4 / 24 h / 20 °C View Scheme
参考文献
Uraguchi, Daisuke; Terada, Masahiro
Journal of the American Chemical Society, 2004 , vol. 126, # 17 p. 5356 - 5357
反应条件
acetic acid; sodium nitrite in dimethyl sulfoxide T=60°C; Nef reaction; 14 h; Title compound not separated from byproducts.;
参考文献
Xu, Xuenong; Furukawa, Tomihiro; Okino, Tomotaka; Miyabe, Hideto; Takemoto, Yoshiji
Chemistry - A European Journal, 2006 , vol. 12, # 2 p. 466 - 476
反应条件
sec.-butyllithium; (-)-sparteine in hexane T=-78°C; 0.333333 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Barberis, Claude; Voyer, Normand; Roby, Johanne; Chenard, Sylvain; Tremblay, Martin; Labrie, Philippe
Tetrahedron, 2001 , vol. 57, # 15 p. 2965 - 2972
反应条件
potassium hydroxide; potassium permanganate in water; tert-butyl alcohol
参考文献
Morita; Nagasawa; Yahiro; Matsunaga; Kunieda
Organic letters, 2001 , vol. 3, # 6 p. 897 - 899
