反应条件
1: Fmoc-Gly-Novasynreg; TGT resin With piperidine in N,N-dimethyl-formamide T=20°C; 0.333333 h; solid phase reaction; 2: Nα-Fmoc-N(im)-trityl-L-histidine With n-ethyl morpholine; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate in N,N-dimethyl-formamide 2 h; solid phase reaction; 3: N-(9-fluorenylmethoxycarbonyl)glycine; N-(fluoren-9-ylmethoxycarbonyl)-L-Val; fmoc-L-Ser(TBu)-OH; fmoc-Gln(Trt)-OH; Nα-Fmoc-N(im)-trityl-L-histidine Further stages;
参考文献
Kuczer, Mariola; Dziubasik, Katarzyna; Midak-Siewirska, Anna; Zahorska, Renata; Luczak, Miroslaw; Konopinska, Danuta
Journal of Peptide Science, 2010 , vol. 16, # 4 p. 186 - 189
