N-(4-氯苯基)-对甲苯磺酰胺合成路线 （共 33 条）
反应条件
AlCl3, aluminium chloride in benzene
T=80°C; 1 h; Inert atmosphere; Reagent/catalystSolventTemperatureTime;
参考文献
Bunce, Richard A.; Cain, Nicholas R.; Cooper, John G.
Organic Preparations and Procedures International, 2013 , vol. 45, # 1 p. 28 - 43
反应条件
n-butyllithium; 4-methoxy-aniline in tetrahydrofuran; hexane
1.5 h; Ambient temperature;
参考文献
Ono; Todoriki; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 4 p. 866 - 873
反应条件
copper(l) iodide; caesium carbonate in N,N-dimethyl-formamide
T=135°C; 24 h;
参考文献
Teo, Yong-Chua; Yong, Fui-Fong
Synlett, 2011 , # 6 p. 837 - 843
反应条件
potassium tert-butylate in tetrahydrofuran
17 h; Ambient temperature; Yields of byproduct given;
参考文献
Ono; Araya; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 5 p. 1373 - 1378
反应条件
1: cyanic acid sodium salt / water / 0.17 h / |Reflux
2: potassium carbonate / water / 4 h / |Reflux
View Scheme
参考文献
Azarifar, Davood; Soleimanei, Fatemeh
RSC Advances, 2014 , vol. 4, # 24 p. 12119 - 12126
反应条件
1: 100 percent / sodium hydrogentelluide (NaTeH) / ethanol; diethyl ether / 0.25 h / Ambient temperature
2: tosylation
View Scheme
参考文献
Suzuki, Hitomi; Takaoka, Koji
Chemistry Letters, 1984 , p. 1733 - 1736
反应条件
sodium ethanolate in tetrahydrofuran
3 h; Heating;
参考文献
Ono; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 3 p. 590 - 596
反应条件
sodium in tetrahydrofuran
24 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Ono; Aoki; Tamura
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 5 p. 1379 - 1388
反应条件
1.1: magnesium / diethyl ether / 0.17 h / |Inert atmosphere; |Reflux
1.2: 0.5 h / |Inert atmosphere; |Heating
2.1: AlCl3, aluminium chloride / benzene / 1 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Bunce, Richard A.; Cain, Nicholas R.; Cooper, John G.
Organic Preparations and Procedures International, 2013 , vol. 45, # 1 p. 28 - 43
反应条件
1.1: acetic acid / 20 h / |Inert atmosphere; |Reflux
2.1: pyridine / 0.5 h / 20 - 100 °C / |Inert atmosphere
3.1: magnesium / diethyl ether / 0.17 h / |Inert atmosphere; |Reflux
3.2: 0.5 h / |Inert atmosphere; |Heating
4.1: AlCl3, aluminium chloride / benzene / 1 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Bunce, Richard A.; Cain, Nicholas R.; Cooper, John G.
Organic Preparations and Procedures International, 2013 , vol. 45, # 1 p. 28 - 43
