2-溴-N-(P-甲苯磺酰)吡咯合成路线 （共 4 条）
反应条件
1: 2-bromo-1H-pyrrole With sodium hydride in N,N-dimethyl-formamide T=-20°C; Metallation; 3 h; 2: p-toluenesulfonyl chloride in tetrahydrofuran T=-20°C; Tosylation; 1 h;
参考文献
Cho, Dae Won; Fujitsuka, Mamoru; Ryu, Jung Ho; Lee, Myoung Hee; Kim, Hwan Kyu; Majima, Tetsuro; Im, Chan
Chemical Communications, 2012 , vol. 48, # 28 p. 3424 - 3426
反应条件
n-butyllithium; dimethyl-(4-nitro-buta-1,3-dienyl)-amine in tetrahydrofuran; pentane T=-78 - 20°C; Dehalogenation;
参考文献
Koike, Takeshi; Shinohara, Yoshifumi; Nishimura, Takeshi; Hagiwara, Masanori; Tobinaga, Seisho; Takeuchi, Naoki
Heterocycles, 2000 , vol. 53, # 6 p. 1351 - 1359
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; toluene
Suzuki coupling; Heating;
参考文献
Knight, Lea W.; Huffman, John W.; Isherwood, Matthew L.
Synlett, 2003 , # 13 p. 1993 - 1996
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; toluene
Suzuki coupling; 6 h; Heating;
参考文献
Knight, Lea W.; Huffman, John W.; Isherwood, Matthew L.
Synlett, 2003 , # 13 p. 1993 - 1996
