2,4,6-三甲基苯甲腈N-氧化物合成路线 （共 55 条）
反应条件
1: 80 percent / benzene / 45 h / 20 °C 2: 82 percent / concd. aq. hydrochlorid acid / dimethylsulfoxide / 2 h / 90 - 100 °C View Scheme
参考文献
Esipenko, A. A.; Fetyukhin, V. N.; Kramarenko, F. G.; Chernega, A. N.; Samarai, L. I.; Pirozhenko, V. V.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 6.2 p. 1101 - 1108
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 6 p. 1262 - 1270
反应条件
(2S)-N-methyl-1-phenylpropan-2-amine hydrate 1.) CHCl3, 0 - 5 deg C, 1 h, then room temp., 10 h; Yield given. Multistep reaction;
参考文献
Rao, Kakulapati Rama; Srinivasan, Tiruchirapally Natesan; Sattur, Prahlad Balvantrao
Heterocycles, 1988 , vol. 27, # 3 p. 683 - 686
反应条件
lithium diisopropyl amide
multistep reaction: various reagents; Product distribution;
参考文献
Schaumann, Ernst; Ruehter, Gerd
Chemische Berichte, 1988 , vol. 121, p. 1159 - 1164
反应条件
1: Et3N, PhCH2SO2Cl / diethyl ether
View Scheme
参考文献
Truce,W.E.; Naik,A.R.
Canadian Journal of Chemistry, 1966 , vol. 44, p. 297 - 305
反应条件
trifluoroacetic acid
1.) benzene, rt, 3 h; 2.) benzene, rt, overnight; Yield given. Multistep reaction;
参考文献
Taylor, Giles A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1181 - 1184
参考文献
Streith,J. et al.
Tetrahedron, 1977 , vol. 33, p. 1349 - 1351
参考文献
Streith,J. et al.
Tetrahedron, 1977 , vol. 33, p. 1349 - 1351
反应条件
T=70°C; Rate constant;
参考文献
Beltrame, Paolo; Gelli, Gioanna; Loi, Aldo
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1609 - 1612
参考文献
Schmidpeter,A.; von Criegern,T.
Chemische Berichte, 1979 , vol. 112, p. 3472 - 3479
反应条件
triethylamine in chloroform
22 h; Ambient temperature;
参考文献
Fernandez, M. Pilar; Gonzalez, Beatriz; Pardo, Mercedes; Soto, Jose L.
Anales de Quimica, 1994 , vol. 90, # 7-8 p. 477 - 482
