6-甲氧基-2-甲基苯并呋喃合成路线 （共 9 条）
反应条件
copper(l) iodide; N,N,N',N'-tetramethylguanidine; bis-triphenylphosphine-palladium(II) chloride in DMF (N,N-dimethyl-formamide) T=-78 - 20°C; 18 h;
参考文献
PFIZER INC.
Patent: WO2003/106462 A1, 2003 ;
Location in patent: Page 50; 51 ;
反应条件
sodium carbonate; p-benozquinone; dichloro bis(acetonitrile) palladium(II) in 1,4-dioxane T=80°C; Title compound not separated from byproducts;
参考文献
So, Won Youn; Jeong, Im Eom
Organic Letters, 2005 , vol. 7, # 15 p. 3355 - 3358
反应条件
1: K2CO3 / dimethylformamide / 0 - 20 °C 2: 1,4-benzoquinone; Na2CO3 / Pd(MeCN)2Cl2 / dioxane / 80 °C View Scheme
参考文献
So, Won Youn; Jeong, Im Eom
Organic Letters, 2005 , vol. 7, # 15 p. 3355 - 3358
反应条件
sulfuric acid in ethanol 3 h; Heating; Yield given. Yields of byproduct given;
参考文献
Alemagna, Andreina; Baldoli, Clara; Buttero, Paola Del; Licandro, Emanuela; Maiorana, Stefano
Journal of the Chemical Society, Chemical Communications, 1985 , # 7 p. 417 - 418
反应条件
sodium hydroxide; DCN in water; acetonitrile IrradiationpH = 10; Yield given;
参考文献
Pandey, G.; Krishna, A.; Bhalerao, U.T.
Tetrahedron Letters, 1989 , vol. 30, # 14 p. 1867 - 1870
反应条件
cesium fluoride; N,N-diethylaniline 8 h; Heating;
参考文献
Ishikawa, Tsutomu; Nagai, Keiko; Ohkubo, Naoko; Ishii, Hisashi
Heterocycles, 1994 , vol. 39, # 1 p. 371 - 380
反应条件
boron tribromide in dichloromethane
T=-5 - 0°C; 1.5 h;
参考文献
PFIZER INC.
Patent: WO2005/63739 A1, 2005 ;
Location in patent: Page/Page column 129 ;
WO 2005/063739 A1
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US2004/9965 A1, 2004 ;
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US2004/9965 A1, 2004 ;
