咪唑[1,2-a]吡啶-3-丙酮合成路线 （共 4 条）
反应条件
1: imidazo(1,2-a)-pyridine With AlCl3, aluminium chloride in carbon disulfide T=0 - 20°C; Inert atmosphere; 2: acetic anhydride in carbon disulfide 5.5 h; Reflux;
参考文献
Melvin, JR., Lawrence S.; Graupe, Michael; Venkataramani, Chandrasekar
Patent: US2010/29638 A1, 2010 ;
Location in patent: Page/Page column 65 ;
US 20100029638 A1
反应条件
1: 2-aminopyridine With N,N-dimethyl-formamide dimethyl acetal in toluene Reflux; 2: 1-bromo-2-propanone in ethanol Reflux;
参考文献
Matsufuji, Tetsuyoshi; Ikeda, Mika; Naito, Asuka; Hirouchi, Masakazu; Kanda, Shoichi; Izumi, Masanori; Harada, Jun; Shinozuka, Tsuyoshi
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2560 - 2565
反应条件
1: chloroform / unter Druck 2: aqueous K2CO3 View Scheme
参考文献
Schilling et al.
Chemische Berichte, 1955 , vol. 88, p. 1093,1100
参考文献
Schilling et al.
Chemische Berichte, 1955 , vol. 88, p. 1093,1100
