2,5-二甲基-呋喃-3-羧酸乙酯合成路线 （共 29 条）
反应条件
sodium hydroxide in water 5 h; Reflux;
参考文献
Wang, Gang-Qiang; Guan, Zhi; Tang, Rong-Chang; Ostojic, Zeljko; Jones, T. Nicholas; Wu, Ting-Ting; He, Yan-Hong
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 3 p. 540 - 543
反应条件
lithium aluminium tetrahydride in diethyl ether 10 h; Ambient temperature;
参考文献
Trahanovsky, Walter S.; Chou, Chin-Hsing; Cassady, Timothy J.
Journal of Organic Chemistry, 1994 , vol. 59, # 9 p. 2613 - 2615
反应条件
hydrazine hydrate T=140°C;
参考文献
Stevenson; Johnson
Journal of the American Chemical Society, 1937 , vol. 59, p. 2525,2529
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in benzene
T=60°C; 12 h;
参考文献
Tang; Huang, Xian; Xu, Wei-Ming
Tetrahedron, 2004 , vol. 60, # 44 p. 9963 - 9969
反应条件
hydrogenchloride in water
T=100°C; Paal-Knorr cyclization; P=760.051 Torr; 2 h; Microwave irradiation;
参考文献
Wang, Gang-Qiang; Guan, Zhi; Tang, Rong-Chang; Ostojic, Zeljko; Jones, T. Nicholas; Wu, Ting-Ting; He, Yan-Hong
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 3 p. 540 - 543
反应条件
N-bromosuccinmide in tetrachloromethane
参考文献
Kretchmer; Richard Allan; Laitar; Robert Anton
Patent: US4025537 A1, 1977 ;
反应条件
indium trifluoromethanesulfonate in toluene
T=20°C; 4 h;
参考文献
Tsuji, Hayato; Yamagata, Ken-Ichi; Ueda, Yasuyuki; Nakamura, Eiichi
Synlett, 2011 , # 7 p. 1015 - 1017
反应条件
sodium chloride; toluene-4-sulfonic acid in ethanol; ethyl acetate; N,N-dimethyl-formamide; mineral oil
参考文献
Sankyo Company, Limited
Patent: US5977168 A1, 1999 ;
反应条件
1.1: polymer-supported selenium bromide resin / tetrahydrofuran / 3 h / 20 °C
1.2: NaI; MeI / dimethylformamide / 18 h / 75 °C
2.1: 71 percent / DBU / benzene / 12 h / 60 °C
View Scheme
参考文献
Tang; Huang, Xian; Xu, Wei-Ming
Tetrahedron, 2004 , vol. 60, # 44 p. 9963 - 9969
反应条件
potassium carbonate in dimethyl sulfoxide
T=115°C; 2 h;
参考文献
Akhmedov, Sh. T.; Sadykhov, N. S.; Ismailov, V. M.; Akhundova, M. A.; Sadovaya, N. K.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 12 p. 1291 - 1295
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 12 p. 1602 - 1606
