(S)-(-)-3-丁炔-2-醇合成路线 （共 18 条）
反应条件
0.5 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Akazome, Motohiro; Toma, Shusaku; Horiguchi, Tatsunori; Megumi, Ken; Matsumoto, Shoji
Tetrahedron, 2011 , vol. 67, # 16 p. 2844 - 2848
反应条件
Prapine-Borane T=25°C; 12 h; vaious ketones, other reagent, other time; Product distribution;
参考文献
Brown, Herbert C.; Pai, G. Ganesh
Journal of Organic Chemistry, 1985 , vol. 50, # 9 p. 1384 - 1394
反应条件
hydrogenchloride; sodium hydroxide 1.) water, 2.) 0 deg C, 30 min, room temperature, 2 h; Yield given. Multistep reaction;
参考文献
Smith, Roger A.; White, Robert L.; Krantz, Allen
Journal of Medicinal Chemistry, 1988 , vol. 31, # 8 p. 1558 - 1566
反应条件
toluene-4-sulfonic acid in dichloromethane 1 h;
参考文献
Noe, Christian R.; Knollmueller, Max; Oberhauser, Berndt; Steinbauer, Gerhard; Wagner, Ernst
Chemische Berichte, 1986 , vol. 119, # 2 p. 729 - 743
反应条件
lithium aluminium tetrahydride; Darvon-OH; tetrabutyl ammonium fluoride 2) THF; Multistep reaction. Title compound not separated from byproducts;
参考文献
Marshall, James A.; Wang, Xiao-jun
Journal of Organic Chemistry, 1992 , vol. 57, # 4 p. 1242 - 1252
反应条件
lithium amide in tetrahydrofuran; ammonia T=-78°C; other base and conditions; Product distribution;
参考文献
Ito, Takayori; Okamoto, Sentaro; Sato, Fumie
Tetrahedron Letters, 1989 , vol. 30, # 50 p. 7083 - 7086
反应条件
(R)-1-phenyl-ethyl-amine Resolution of racemate; optical yield given as percent ee;
参考文献
Abbate, Sergio; Longhi, Giovanna; Gangemi, Fabrizio; Gangemi, Roberto; Superchi, Stefano; Caporusso, Anna Maria; Ruzziconi, Renzo
Chirality, 2011 , vol. 23, # 9 p. 841 - 849
反应条件
hydrogen; Lindlar's catalyst in diethylene glycol P=750.06 Torr; 312 h;
参考文献
Hoeck, Stefan; Borschberg, Hans-Juerg
Helvetica Chimica Acta, 2006 , vol. 89, # 3 p. 542 - 557
