2-乙基-苯并[d][1,3]噁嗪-4-酮合成路线 （共 13 条）
反应条件
T=160°C; 0.166667 h; Irradiation;
参考文献
Kostakis, Ioannis K.; Elomri, Abdelhakim; Seguin, Elisabeth; Iannelli, Mauro; Besson, Thierry
Tetrahedron Letters, 2007 , vol. 48, # 38 p. 6609 - 6613
反应条件
DMEG; triethylamine in dichloromethane T=20°C; Dehydration; Cyclization; 18 h;
参考文献
Isobe, Toshio; Ishikawa, Tsutomu
Journal of Organic Chemistry, 1999 , vol. 64, # 19 p. 6989 - 6992
反应条件
3 h; Heating / reflux;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2004/111014 A1, 2004 ;
Location in patent: Page/Page column 263-264 ;
WO 2004/111014 A1
反应条件
1: in dichloromethane Reflux; 2: With acetic anhydride Reflux;
参考文献
ACHE LABORATORIOS FARMACEUTICOS S.A.; ACHE INTERNATIONAL (BVI) LTD.; FREIRE TORRES RUSSO, Valter; MANNOCHIO DE SOUZA RUSSO, Elisa
Patent: WO2012/37634 A1, 2012 ;
Location in patent: Page/Page column 30-31 ;
WO 2012/037634 A1
反应条件
triphenyl phosphite in pyridine T=150°C; 0.166667 h; microwave irradiation;
参考文献
Liu, Ji-Feng; Lee, Jaekyoo; Dalton, Audra M.; Bi, Grace; Yu, Libing; Baldino, Carmen M.; McElory, Eric; Brown, Matt
Tetrahedron Letters, 2005 , vol. 46, # 8 p. 1241 - 1244
反应条件
1: Et3N / CH2Cl2 / 20 °C 2: 72 percent / cyanuric chloride; Et3N / toluene / Heating View Scheme
参考文献
Clemence, Francois; Martret, Odile Le; Collard, Jeannine
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 1345 - 1353
参考文献
Khajavi, Mohammad S.; Montazari, Nasser; Sadat Hosseini
Journal of Chemical Research - Part S, 1997 , # 8 p. 286 - 287
反应条件
in DMF (N,N-dimethyl-formamide) T=140°C; 10 h;
参考文献
Banyu Pharmaceutical Co., Ltd.
Patent: US2005/182045 A1, 2005 ;
Location in patent: Page/Page column 32 ;
US 20050182045 A1
反应条件
ammonium acetate; acetic acid 0.0833333 h; microwave irradiation;
参考文献
Kostakis, Ioannis K.; Elomri, Abdelhakim; Seguin, Elisabeth; Iannelli, Mauro; Besson, Thierry
Tetrahedron Letters, 2007 , vol. 48, # 38 p. 6609 - 6613
参考文献
ACHE LABORATORIOS FARMACEUTICOS S.A.; ACHE INTERNATIONAL (BVI) LTD.; FREIRE TORRES RUSSO, Valter; MANNOCHIO DE SOUZA RUSSO, Elisa
Patent: WO2012/37634 A1, 2012 ;
Location in patent: Page/Page column 31 ;
WO 2012/037634 A1
