1.1: 70 percent / aq. KHCO3 / 36 h / 23 °C / 49403.3 Torr 2.1: AD-mix-α; CH3SO2NH2; H2O / 2-methyl-propan-2-ol / 36 h / 0 °C 2.2: H2 / Pd-CaCO3 / tetrahydrofuran / 0.67 h / 23 °C / 760.05 Torr 3.1: Et3N / CH2Cl2 / 1 h / 0 °C 4.1: i-Bu2AlH / toluene / 1 h / -78 °C 5.1: HMPA / tetrahydrofuran / 1 h / -25 °C 6.1: aq. LiOH / tetrahydrofuran View Scheme

1.1: 70 percent / aq. KHCO3 / 36 h / 23 °C / 49403.3 Torr 2.1: AD-mix-β; CH3SO2NH2; H2O / 2-methyl-propan-2-ol / 36 h / 0 °C 2.2: H2 / Pd-CaCO3 / tetrahydrofuran / 0.67 h / 23 °C / 760.05 Torr 3.1: Et3N / CH2Cl2 / 1 h / 0 °C 4.1: i-Bu2AlH / toluene / 1 h / -78 °C 5.1: 72 percent / HMPA / tetrahydrofuran / 1 h / -25 °C 6.1: aq. LiOH / tetrahydrofuran View Scheme