2,9-二氯-1,10-菲罗啉合成路线 （共 23 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in water; toluene
T=95°C; 18 h; Inert atmosphere;
参考文献
Pirtsch, Michael; Paria, Suva; Matsuno, Taisuke; Isobe, Hiroyuki; Reiser, Oliver
Chemistry - A European Journal, 2012 , vol. 18, # 24 p. 7336 - 7340
反应条件
ammonia in various solvent(s)
T=160°C;
参考文献
Pijper; Van der Goot; Timmerman; Nauta Th.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 399 - 404
反应条件
1: With phosphorus tribromide
T=165°C; 7 h; Inert atmosphereNeat (no solvent);
2: With sodium hydrogencarbonate in water
参考文献
Sumitomo Chemical Company, Limited
Patent: EP2360162 A1, 2011 ;
Location in patent: Page/Page column 43 ;
