5-叔丁氧基羰基氨基-苯并[b]噻吩-2-羧酸合成路线 （共 4 条）
反应条件
sodium hydroxide in methanol T=60°C; 4 h;
参考文献
Boger, Dale L.; Fink, Brian E.; Hedrick, Michael P.
Journal of the American Chemical Society, 2000 , vol. 122, # 27 p. 6382 - 6394
反应条件
1.1: Fe / methanol / 12 h / Heating 1.2: 87 percent / aq. HCl / methanol / 2 h / Heating 2.1: 90 percent / tetrahydrofuran / 16 h / Heating 3.1: 89 percent / aq. NaOH / methanol / 4 h / 60 °C View Scheme
参考文献
Boger, Dale L.; Fink, Brian E.; Hedrick, Michael P.
Journal of the American Chemical Society, 2000 , vol. 122, # 27 p. 6382 - 6394
反应条件
1: 90 percent / tetrahydrofuran / 16 h / Heating 2: 89 percent / aq. NaOH / methanol / 4 h / 60 °C View Scheme
参考文献
Boger, Dale L.; Fink, Brian E.; Hedrick, Michael P.
Journal of the American Chemical Society, 2000 , vol. 122, # 27 p. 6382 - 6394
反应条件
1.1: 66 percent / K2CO3 / dimethylformamide / 20 h / 25 °C 2.1: Fe / methanol / 12 h / Heating 2.2: 87 percent / aq. HCl / methanol / 2 h / Heating 3.1: 90 percent / tetrahydrofuran / 16 h / Heating 4.1: 89 percent / aq. NaOH / methanol / 4 h / 60 °C View Scheme
参考文献
Boger, Dale L.; Fink, Brian E.; Hedrick, Michael P.
Journal of the American Chemical Society, 2000 , vol. 122, # 27 p. 6382 - 6394
