1-Boc-氨基-2,2-二甲基1,3-丙烷二胺合成路线 （共 5 条）
反应条件
in acetonitrile 2 h; Ambient temperature;
参考文献
Kureha Chemical Industry Co., Ltd.
Patent: EP1550657 A1, 2005 ;
Location in patent: Page/Page column 46 ;
反应条件
water; sodium hydroxide in methanol T=20 - 50°C; 3 h;
参考文献
Jenkins, Thomas E.; Husfeld, Craig O.
Patent: US2012/178772 A1, 2012 ;
Location in patent: Page/Page column 27 ;
反应条件
in 1,4-dioxane T=20°C; Acylation; 16 h;
参考文献
Marmillon, Christelle; Bompart, Jacques; Calas, Michele; Escale, Roger; Bonnet, Pierre-Antoine
Heterocycles, 2000 , vol. 53, # 6 p. 1317 - 1328
反应条件
1: tetrahydrofuran / 14.5 h / 20 °C / Cooling with ice 2: tetrahydrofuran / 15.25 h / 20 °C / Cooling with ice 3: sodium hydroxide; water / methanol / 3 h / 20 - 50 °C View Scheme
参考文献
Jenkins, Thomas E.; Husfeld, Craig O.
Patent: US2012/178772 A1, 2012 ;
反应条件
1: tetrahydrofuran / 15.25 h / 20 °C / Cooling with ice 2: sodium hydroxide; water / methanol / 3 h / 20 - 50 °C View Scheme
参考文献
Jenkins, Thomas E.; Husfeld, Craig O.
Patent: US2012/178772 A1, 2012 ;
