1: ethyl phenylsulphonylacetate With sodium hydride in tetrahydrofuran T=20°C; 0.166667 h; 2: o-(trimethylsilyl)phenyl triflate; acrylic acid methyl ester With potassium fluoride; 18-crown-6 ether in tetrahydrofuran T=65°C; Further stages. Title compound not separated from byproducts.;
参考文献
Huang, Xian; Xue, Jian
Journal of Organic Chemistry, 2007 , vol. 72, # 10 p. 3965 - 3968
Candida antarctica lipase B Novozyme 435 in 1,4-dioxane T=30°C; Michael addition; 1 h; KineticsProduct distribution; Further Variations:ReagentsSolventsTemperatureseduct and reagent amount;
参考文献
Torre, Oliver; Gotor-Fernandez, Vicente; Alfonso, Ignacio; Garcia-Alles, Luis Fernando; Gotor, Vicente
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 7-8 p. 1007 - 1014