1,2-苯并异噻唑-3-乙酸合成路线 （共 8 条）
反应条件
hydroxylamine hydrochloride; sodium ethanolate in ethanol T=75 - 80°C; 6 h;
参考文献
Sato, Kazuo; Honma, Toyokuni; Sugai, Soji
Agricultural and Biological Chemistry, 1985 , vol. 49, # 12 p. 3563 - 3568
反应条件
sodium hydroxide in ethanol Heating;
参考文献
Carrington,D.E.L. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 3006 - 3010
反应条件
sodium hydroxide in ethanol Heating;
参考文献
Vicini, Paola; Incerti, Matteo; Amoretti, Loredana; Ballabeni, Vigilio; Tognolini, Massimiliano; Barocelli, Elisabetta
Farmaco, 2002 , vol. 57, # 5 p. 363 - 367
反应条件
1: NaOEt, urea / ethanol / Heating 2: aq. NaOH / ethanol / Heating View Scheme
参考文献
Carrington,D.E.L. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 3006 - 3010
反应条件
1: 165 °C 2: aq. H2O2, AcOH / 100 °C View Scheme
参考文献
Carrington,D.E.L. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 3006 - 3010
参考文献
Uno; Kurokawa
Chemical and Pharmaceutical Bulletin, 1978 , vol. 26, # 12 p. 3888 - 3891
反应条件
1: With bromine; acetic acid
2: With sulfuric acid
Reflux;
参考文献
Incerti, Matteo; Acquotti, Domenico; Vicini, Paola
Magnetic Resonance in Chemistry, 2008 , vol. 46, # 12 p. 1175 - 1179
参考文献
Carrington,D.E.L. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1972 , p. 3006 - 3010
