反应条件
1.1: aq. KOH / methanol / 15 h / 20 °C
1.2: oxalyl chloride; DMF / diethyl ether / 3 h / 20 °C
2.1: 77 percent / aq. K2CO3; n-Bu3NHSO4 / benzene / 20 h / 20 °C
3.1: NaH / dimethylsulfoxide / 3 h / 20 °C
3.2: aq. oxalic acid / 0 °C
3.3: AcOH; conc. HCl / 1.5 h
4.1: (COCl)2; DIPEA; DMSO / CH2Cl2 / 0.5 h / -78 - 20 °C
5.1: HMPA / tetrahydrofuran / 16 h / -85 - 20 °C
View Scheme
参考文献
Domon; Uguen
Tetrahedron Letters, 2000 , vol. 41, # 29 p. 5501 - 5505
