N-[4-[2,2,2-三氟-1-羟基-1-(三氟甲基)乙基]苯基]-2-噻吩磺酰胺合成路线 （共 2 条）
反应条件
2,6-dimethylpyridine in acetone T=80°C; 24 h; Inert atmosphere; Product distribution / selectivity;
参考文献
GRIFFIN, Patrick R.; ROUSH, William R.; KUMAR, Naresh; NUHANT, Philippe; BURRIS, Thomas; SOLT, Laura
Patent: WO2011/115892 A1, 2011 ;
Location in patent: Page/Page column 6; 45; 46 ;
WO 2011/115892 A1
反应条件
1: toluene-4-sulfonic acid / 130 °C / Neat (no solvent) 2: 2,6-dimethylpyridine / acetone / 24 h / 80 °C / Inert atmosphere View Scheme
参考文献
GRIFFIN, Patrick R.; ROUSH, William R.; KUMAR, Naresh; NUHANT, Philippe; BURRIS, Thomas; SOLT, Laura
Patent: WO2011/115892 A1, 2011 ;
WO 2011/115892 A1
