4-氰基-2,2-二乙基丁醛合成路线 （共 6 条）
反应条件
potassium hydroxide in water T=60°C;
参考文献
Rodrigues, Catarina A.B.; De Matos, Marta Norton; Guerreiro, Bruno M.H.; Goncalves, Ana M.L.; Romao, Carlos C.; Afonso, Carlos A.M.
Tetrahedron Letters, 2011 , vol. 52, # 22 p. 2803 - 2807
参考文献
Polak's Frutal Works B.V.
Patent: US4288350 A1, 1981 ;
反应条件
potassium hydroxide unter kontinuierlicher Abtrennung des freigesetzten Wassers;
参考文献
Bruson; Riener
Journal of the American Chemical Society, 1944 , vol. 66, p. 57
Full Text Show Details
Resinous Prod.and Chem.Co.
Patent: US2437906 , 1945 ;
Full Text Show Details
Resinous Prod.and Chem.Co.
Patent: US2342607 , 1943 ;
Full Text Show Details
Resinous Prod.and Chem.Co.
Patent: US2353687 , 1942 ;
反应条件
1: 93 percent / p-toluene sulfonic acid / benzene / 3 h / Heating
2: LiAlH4 / tetrahydrofuran / 3 h / Heating
3: 10percent aq. HCl / 1 h / Ambient temperature
4: 10percent aq. NaOH / 1 h / Ambient temperature; pH = 9
5: 97 percent / hydrogen / 5percent Pd/C / aq. ethanol / 3 h / 2327.2 Torr
6: 90 percent / toluene / 2 h / Ambient temperature
View Scheme
参考文献
Liebowitz; Belair; Witiak; Lednicer
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 5 p. 439 - 444
反应条件
cyclohexyl hydroperoxide
T=130°C;
参考文献
Roehm and Haas Co.
Patent: US2458337 , 1948 ;
参考文献
Rohm and Haas Co.
Patent: US2458337 , 1948 ;
