1.1: lithium borohydride / methanol; diethyl ether / 20 °C 2.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water / 20 °C 3.1: Fetizon's reagent (silver carbonate on celite) / benzene / 4 h / Reflux 4.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 4.2: 22 h / -78 - -50 °C / Inert atmosphere 5.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 6.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water / 20 °C 2.1: Fetizon's reagent (silver carbonate on celite) / benzene / 4 h / Reflux 3.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 3.2: 22 h / -78 - -50 °C / Inert atmosphere 4.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 5.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: potassium hexamethylsilazane / tetrahydrofuran; hexane / 1.17 h / -72 °C / Inert atmosphere 1.2: 2 h / -72 °C / Inert atmosphere 2.1: lithium borohydride / methanol; diethyl ether / 20 °C 3.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water / 20 °C 4.1: Fetizon's reagent (silver carbonate on celite) / benzene / 4 h / Reflux 5.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 5.2: 22 h / -78 - -50 °C / Inert atmosphere 6.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 7.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 2.1: potassium carbonate / acetone / Inert atmosphere; Reflux 3.1: water; potassium hydroxide / methanol / 70 °C 4.1: triethylamine / tetrahydrofuran / -70 - 0 °C / Inert atmosphere 5.1: n-butyllithium / tetrahydrofuran; hexane / -70 °C / Inert atmosphere 5.2: -70 - 0 °C / Inert atmosphere 6.1: potassium hexamethylsilazane / tetrahydrofuran; hexane / 1.17 h / -72 °C / Inert atmosphere 6.2: 2 h / -72 °C / Inert atmosphere 7.1: lithium borohydride / methanol; diethyl ether / 20 °C 8.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water / 20 °C 9.1: Fetizon's reagent (silver carbonate on celite) / benzene / 4 h / Reflux 10.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 10.2: 22 h / -78 - -50 °C / Inert atmosphere 11.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 12.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: sodium tetrahydroborate / methanol; dichloromethane / 1 h / 20 °C 2.1: 1H-imidazole; iodine; triphenylphosphine / tetrahydrofuran / 0.83 h / 0 °C 3.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 3.2: 22 h / -78 - -50 °C / Inert atmosphere 4.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 5.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: potassium carbonate / acetone / Inert atmosphere; Reflux 2.1: water; potassium hydroxide / methanol / 70 °C 3.1: triethylamine / tetrahydrofuran / -70 - 0 °C / Inert atmosphere 4.1: n-butyllithium / tetrahydrofuran; hexane / -70 °C / Inert atmosphere 4.2: -70 - 0 °C / Inert atmosphere 5.1: potassium hexamethylsilazane / tetrahydrofuran; hexane / 1.17 h / -72 °C / Inert atmosphere 5.2: 2 h / -72 °C / Inert atmosphere 6.1: lithium borohydride / methanol; diethyl ether / 20 °C 7.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water / 20 °C 8.1: Fetizon's reagent (silver carbonate on celite) / benzene / 4 h / Reflux 9.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 9.2: 22 h / -78 - -50 °C / Inert atmosphere 10.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 11.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: 1H-imidazole; iodine; triphenylphosphine / tetrahydrofuran / 0.83 h / 0 °C 2.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 2.2: 22 h / -78 - -50 °C / Inert atmosphere 3.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 4.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: triethylamine / tetrahydrofuran / -70 - 0 °C / Inert atmosphere 2.1: n-butyllithium / tetrahydrofuran; hexane / -70 °C / Inert atmosphere 2.2: -70 - 0 °C / Inert atmosphere 3.1: potassium hexamethylsilazane / tetrahydrofuran; hexane / 1.17 h / -72 °C / Inert atmosphere 3.2: 2 h / -72 °C / Inert atmosphere 4.1: lithium borohydride / methanol; diethyl ether / 20 °C 5.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water / 20 °C 6.1: Fetizon's reagent (silver carbonate on celite) / benzene / 4 h / Reflux 7.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 7.2: 22 h / -78 - -50 °C / Inert atmosphere 8.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 9.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: potassium carbonate / ethanol / 20 °C 2.1: sodium tetrahydroborate / methanol; dichloromethane / 1 h / 20 °C 3.1: 1H-imidazole; iodine; triphenylphosphine / tetrahydrofuran / 0.83 h / 0 °C 4.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 4.2: 22 h / -78 - -50 °C / Inert atmosphere 5.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 6.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme

1.1: water; potassium hydroxide / methanol / 70 °C 2.1: triethylamine / tetrahydrofuran / -70 - 0 °C / Inert atmosphere 3.1: n-butyllithium / tetrahydrofuran; hexane / -70 °C / Inert atmosphere 3.2: -70 - 0 °C / Inert atmosphere 4.1: potassium hexamethylsilazane / tetrahydrofuran; hexane / 1.17 h / -72 °C / Inert atmosphere 4.2: 2 h / -72 °C / Inert atmosphere 5.1: lithium borohydride / methanol; diethyl ether / 20 °C 6.1: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water / 20 °C 7.1: Fetizon's reagent (silver carbonate on celite) / benzene / 4 h / Reflux 8.1: sodium hexamethyldisilazane / tetrahydrofuran / 1.25 h / -78 °C / Inert atmosphere 8.2: 22 h / -78 - -50 °C / Inert atmosphere 9.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere 10.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / -15 °C View Scheme