1: DCC / HOBt / dimethylformamide / 0 °C 2: 2.) NaHCO3 / 1.) TFA, room temp., 1.5 hrs; 2.) water, dichloromethane, room temp, 0.5 hr 3: DCC / HOBt / dimethylformamide / 0 °C 4: 2.) NaHCO3 / 1.) TFA, room temp., 1.5 hrs; 2.) water, dichloromethane, room temp, 0.5 hr 5: DCC / HOBt / dimethylformamide / 0 °C 6: 59 percent / anisole, ethyl methyl sulfide, thioanisole / trifluoroacetic acid / 1 h View Scheme