1,5,9-三氮杂环十二烷合成路线 （共 19 条）
反应条件
1: pyridine / acetonitrile 2: KH / dimethylformamide 3: HBr 4: KOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, p. 6365
反应条件
1: 66 percent / KOH, KBr, NaBH4 / toluene / 42.5 h / Ambient temperature 2: 94 percent / aq. H2SO4 / 9.5 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 24, # 21 p. 3109 - 3114
反应条件
1: 73 percent / Cs2CO3 / dimethylformamide / 48 h / 20 °C 2: 81 percent / CsF / dimethylformamide / 24 h / 95 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 8 p. 2722 - 2725
反应条件
formic acid Mechanism;
参考文献
Alder, Roger W.; Colclough, David; Mowlam, Rodney W.
Tetrahedron Letters, 1991 , vol. 32, # 52 p. 7755 - 7758
反应条件
in DMF (N,N-dimethyl-formamide) T=20°C; 48 h;
参考文献
THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW
Patent: WO2005/54241 A2, 2005 ;
Location in patent: Page/Page column 76; 93-94 ;
反应条件
sodium cyanoborohydride
参考文献
Alder, Roger W.; Mowlam, Rodney W.; Vachon, David J.; Weisman, Gary R.
Journal of the Chemical Society, Chemical Communications, 1992 , # 6 p. 507 - 508
反应条件
formic acid Mechanism;
参考文献
Alder, Roger W.; Colclough, David; Mowlam, Rodney W.
Tetrahedron Letters, 1991 , vol. 32, # 52 p. 7755 - 7758
反应条件
tris-(dimethylamino)-phosphine
T=120°C; 96 h;
参考文献
Alexandrova, Anastasia V.; Masek, Tomas; Polyakova, Svetlana M.; Cisarova, Ivana; Saame, Jaan; Leito, Ivo; Lyapkalo, Ilya M.
European Journal of Organic Chemistry, 2013 , # 9 p. 1811 - 1823
反应条件
sodium nitrate; copper(II) nitrate
T=25°C; pH=5; Kinetics; Further Variations:Reagents;
参考文献
Huang, Ching-Hua; Stone, Alan T.
Environmental Science and Technology, 2003 , vol. 37, # 9 p. 1829 - 1837
