2-(4-氯苯基)-5-甲基-4-恶唑羧酸合成路线 (共 7 条)
反应条件
sodium hydroxide in ethanol
参考文献
Tarzia,G. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 263 - 270
反应条件
1: POCl3 / benzene / 4 h / Heating 2: NaOH / ethanol View Scheme
参考文献
Tarzia,G. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 263 - 270
反应条件
1: (i) Zn, aq. H2SO4, (ii) /BRN= 471606/ 2: POCl3 / benzene / 4 h / Heating 3: NaOH / ethanol View Scheme
参考文献
Tarzia,G. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 263 - 270
反应条件
sodium hypobromide in 1,4-dioxane Ambient temperature;
参考文献
Allan,A.W.; Walter,B.H.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 1397 - 1399
反应条件
1: Zn / acetic acid 2: aq. NaOBr / dioxane / Ambient temperature View Scheme
参考文献
Allan,A.W.; Walter,B.H.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 1397 - 1399
反应条件
1: SOCl2 / dimethylformamide
2: NH3
View Scheme
参考文献
Tarzia,G. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 263 - 270
反应条件
thionyl chloride in N,N-dimethyl-formamide
参考文献
Tarzia,G. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 263 - 270