2-(4-甲氧基苯基)-5-甲基-1,3-恶唑-4-羧酸合成路线 （共 4 条）
反应条件
1: With sodium hydroxide; water in ethanol 0.5 h; 2: With hydrogenchloride in ethanol; water
参考文献
Pfizer Inc
Patent: US2005/43292 A1, 2005 ;
Location in patent: Page/Page column 13 ;
反应条件
1: With lithium hydroxide; water in tetrahydrofuran T=20°C; 2: With hydrogenchloride in tetrahydrofuran; water
参考文献
Desroy, Nicolas; Moreau, Francois; Briet, Sophia; Fralliec, Geraldine Le; Floquet, Stephanie; Durant, Lionel; Vongsouthi, Vanida; Gerusz, Vincent; Denis, Alexis; Escaich, Sonia
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 3 p. 1276 - 1289
反应条件
sodium hypobromide in 1,4-dioxane
参考文献
Allan,A.W.; Walter,B.H.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 1397 - 1399
反应条件
1: Zn / acetic acid 2: aq. NaOBr / dioxane View Scheme
参考文献
Allan,A.W.; Walter,B.H.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 1397 - 1399
