1-氨基-2-氰基-1-环戊烯合成路线 （共 16 条）
反应条件
1: With hydroxylamine hydrochloride in ethanol
1 h; Heating / reflux;
2: With sodium hydroxide in ethanol; water; isopropyl alcohol
T=20 - 60°C; 0.5 h;
参考文献
BAYER CHEMICALS AG
Patent: WO2004/50644 A2, 2004 ;
Location in patent: Page/Page column 34 ;
反应条件
ammonium acetate; acetic acid
17 h; Heating;
参考文献
Robinson, J. Michael; Brent, Larry W.; Chau, Chhan; Floyd, Kimberly A.; Gillham, Sherri L.; et al.
Journal of Organic Chemistry, 1992 , vol. 57, # 28 p. 7352 - 7355
反应条件
1: aq. H2SO4 / 20 °C
2: LiOH / H2O; methanol / 2 h / 50 °C
View Scheme
参考文献
Dehli, Juan R.; Gotor, Vicente
Journal of Organic Chemistry, 2002 , vol. 67, # 5 p. 1716 - 1718
反应条件
1: aq. H2SO4 / 20 °C
2: LiOH / H2O; methanol / 2 h / 50 °C
3: 95 percent / NaBH4 / ethanol / 6 h / 20 °C
View Scheme
参考文献
Dehli, Juan R.; Gotor, Vicente
Journal of Organic Chemistry, 2002 , vol. 67, # 5 p. 1716 - 1718
反应条件
hydrogenchloride; sodium tetrahydroborate in methanol
Reduction; 3 h;
参考文献
Atay, Ergun; Blagoeva, Iva B.; Chubb, Francis L.; Edward, John T.; Pojarlieff, Ivan G.; Toteva, Maria M.
Canadian Journal of Chemistry, 2000 , vol. 78, # 1 p. 84 - 94
反应条件
zinc(II) chloride in xylene
Heating;
参考文献
Goncharenko, S. B.; Kaganskii, M.M.; Portnov, Yu. N.; Granik, V. G.
Pharmaceutical Chemistry Journal, 1992 , vol. 26, # 9-10 p. 769 - 772
Khimiko-Farmatsevticheskii Zhurnal, 1992 , vol. 26, # 9-10 p. 83 - 85
