反应条件
1: 50 percent / various solvent(s) / 6 h / 140 - 150 °C 2: 1.) potassium, t-BuOH / 1.) dioxane, 60 deg C, 3 h, 2.) dioxane, RT, overnight 3: 1.) sodium hydride / 1.) DMF, a) RT, 3 h, b) 60 deg C, 1 h, 2.) 2 d 4: 52 percent / anisole, trifluoroacetic acid, concd. H2SO4 / 8 h / 110 °C View Scheme
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
