2-氯烟酸合成路线

参考文献

Elliott, Mark L.; Goddard, Carl J.
Synthetic Communications, 1989 , vol. 19, # 9-10 p. 1505 - 1508

参考文献

Elworthy, Todd R.; Ford, Anthony P. D. W.; Bantle, Gary W.; Morgans Jr., David J.; Ozer, Rachel S.; Palmer, Wylie S.; Repke, David B.; Romero, Magarita; Sandoval, Leticia; Sjogren, Eric B.; Talamas, Francisco X.; Vazquez, Alfredo; Wu, Helen; Arredondo, Nicolas F.; Blue Jr., David R.; DeSousa, Andrea; Gross, Lisa M.; Kava, M. Shannon; Lesnick, John D.; Vimont, Rachel L.; Williams, Timothy J.; Zhu, Quan-Ming; Pfister, Juerg R.; Clarke, David E.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 17 p. 2674 - 2687

2942-59-82-氯烟酸+

141-97-9乙酰乙酸乙酯

1345461-10-0+

35969-51-82-(2-乙氧基-2-氧代乙基)烟酸

参考文献

GLAXO GROUP LIMITED; ATKINSON, Francis Louis; BARKER, Michael David; DOUAULT, Clement; GARTON, Neil Stuart; LIDDLE, John; PATEL, Vipulkumar Kantibhai; PRESTON, Alexander George Steven; WILSON, David Matthew
Patent: WO2011/134971 A1, 2011 ;
Location in patent: Page/Page column 15; 16; 70 ;
WO 2011/134971 A1

35969-51-82-(2-乙氧基-2-氧代乙基)烟酸

参考文献

GLAXO GROUP LIMITED; Atkinson, Francis Louis; Barker, Michael David; Douault, Clement; Garton, Neil Stuart; Liddle, John; Patel, Vipulkumar Kantibhai; Preston, Alexander George Steven; Wilson, David Matthew
Patent: US2013/40984 A1, 2013 ;
Location in patent: Paragraph 0471-0473 ;

67-56-1甲醇+

2942-59-82-氯烟酸

40134-18-72-氯烟酸甲酯

参考文献

IHARA CHEMICAL INDUSTRY CO., LTD.; KUMIAI CHEMICAL INDUSTRY CO., LTD.
Patent: US2011/287937 A1, 2011 ;
Location in patent: Page/Page column 72-73 ;

2942-59-82-氯烟酸

40134-18-72-氯烟酸甲酯

参考文献

CHIESI FARMACEUTICI S.p.A.
Patent: EP349902 A3, 1991 ;

2942-59-82-氯烟酸

40134-18-72-氯烟酸甲酯

参考文献

Doyle, Terrence W.; Karra, Srinivasa; Li, Zujin; Lin, Xu; Mao, John; Qiao, Qi; Xu, Yang
Patent: US2002/119955 A1, 2002 ;

2942-59-82-氯烟酸+

18107-18-1三甲基硅烷化重氮甲烷

40134-18-72-氯烟酸甲酯

参考文献

PFIZER PRODUCTS INC.
Patent: WO2007/31828 A2, 2007 ;
Location in patent: Page/Page column 34 ;

186581-53-3重氮甲烷+

2942-59-82-氯烟酸

40134-18-72-氯烟酸甲酯

参考文献

New, James S.; Yevich, Joseph P.; Temple, Davis L.; New, Kimberly B.; Gross, Sharon M.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 3 p. 618 - 624

2942-59-82-氯烟酸+

74-88-4甲基碘

40134-18-72-氯烟酸甲酯

参考文献

Novartis AG
Patent: US6197798 B1, 2001 ;