1-(4-羟苯基)哌嗪二氰溴化物合成路线 （共 61 条）
反应条件
1: 78 percent / AlCl3 / CH2Cl2 / 8 h / Ambient temperature 2: 85 percent / diethyl ether / 5 °C 3: 100 percent / 2 h / Heating 4: 99 percent / H2 / Pd/C / diethyl ether / 2068.6 Torr 5: 75 percent / PCC, HOAc, Celite, molecular sieve 4A / CH2Cl2 View Scheme
参考文献
Synthetic Communications, , vol. 21, # 1 p. 127 - 132
反应条件
1: 100 percent / 2 h / Heating 2: 99 percent / H2 / Pd/C / diethyl ether / 2068.6 Torr 3: 75 percent / PCC, HOAc, Celite, molecular sieve 4A / CH2Cl2 View Scheme
参考文献
Synthetic Communications, , vol. 21, # 1 p. 127 - 132
反应条件
1: 99 percent / H2 / Pd/C / diethyl ether / 2068.6 Torr 2: 75 percent / PCC, HOAc, Celite, molecular sieve 4A / CH2Cl2 View Scheme
参考文献
Synthetic Communications, , vol. 21, # 1 p. 127 - 132
反应条件
1: 85 percent / diethyl ether / 5 °C 2: 100 percent / 2 h / Heating 3: 99 percent / H2 / Pd/C / diethyl ether / 2068.6 Torr 4: 75 percent / PCC, HOAc, Celite, molecular sieve 4A / CH2Cl2 View Scheme
参考文献
Synthetic Communications, , vol. 21, # 1 p. 127 - 132
反应条件
supercritical carbon dioxide; Amberlyst-15 T=150°C; Friedel-Crafts Alkylation; P=150015 Torr; TemperaturePressure;
参考文献
Organic Process Research and Development, , vol. 9, # 4 p. 451 - 456
反应条件
HPF6 T=25°C; 0.25 h; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 106, # 18 p. 5284 - 5290
反应条件
1: (i) Mg, Et2O, (ii) /BRN= 1100602/ 2: H2, aq. HClO4 / Pd-C / ethyl acetate View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. <II>, p. 255 - 262
参考文献
Journal of the American Chemical Society, , vol. 55, p. 3402,3406
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; [copperl(II)(1,1,1,5,5,5-hexafluoroacetylacetonate)2] monohydrate; palladium diacetate in tert-butyl alcohol T=50°C; 72 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 49, # 26 p. 4447 - 4450
反应条件
4-(N,N-dimethlyamino)pyridine T=140°C; 2 h;
参考文献
Barcelo, Gerard; Grenouillat, Denis; Senet, Jean-Pierre; Sennyey, Gerard
Tetrahedron, 1990 , vol. 46, # 6 p. 1839 - 1848
