1: isopropyl bromide With magnesium in tetrahydrofuran T=0°C; 1 h; 2: 1,4-diazine in tetrahydrofuran T=0°C; 0.25 h; Further stages.;

tert.-butylhydroperoxide; zinc sulfinate; Zn(SO2CF3)2 in water; dimethyl sulfoxide T=20 - 50°C; 12 h; regioselective reaction;

1: 1.) n-BuLi, diisopropylamine / 1.) ether, hexane, 0 deg C, 30 min, 2.) ether, hexane, 0 deg C, 1.5 h 2: 71 percent / CrO3, H2SO4 / acetone; H2O / 0.17 h / 0 °C View Scheme