2-(5-溴-2-甲氧基苯基)乙酸甲酯合成路线 (共 4 条)
反应条件
hydrogenchloride in 1,4-dioxane T=80°C; 6 h;
参考文献
AMIRA PHARMACEUTICALS, INC.
Patent: US2007/173508 A1, 2007 ;
Location in patent: Page/Page column 87 ;
US 20070173508 A1
反应条件
hydrogenchloride anschliessendes Erwaermen und Behandeln des Reaktionsgemisches mit Wasser;
参考文献
Paty
Bulletin de la Societe Chimique de France, 1938 , vol. <5> 5, p. 1676,1682
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl-formamide
T=80°C; 3 h; Inert atmosphere;
参考文献
AMIRA PHARMACEUTICALS, INC.
Patent: WO2009/108720 A2, 2009 ;
Location in patent: Page/Page column 119 ;
WO 2009/108720 A2
参考文献
Eisai Co., Ltd.
Patent: EP1394147 A1, 2004 ;
Location in patent: Page 145 ;