4-溴-1,2,3,4-四氢-1-(4-甲基苯磺酰基)-5H-1-苯并氮杂卓-5-酮合成路线 （共 8 条）
反应条件
pyridinium hydrobromide perbromide in chloroform T=15 - 30°C; 1 h;
参考文献
Tsunoda, Takashi; Yamazaki, Atsuki; Mase, Toshiyasu; Sakamoto, Shuichi
Organic Process Research and Development, 2005 , vol. 9, # 5 p. 593 - 598
反应条件
1: 98 percent / potassium carbonate; potassium iodide / butan-2-one / 12 h / Heating 2: 93 percent / potassium t-butoxide / dimethylformamide / 2 h / 0 - 5 °C 3: 97 percent / acetic acid; cc. HCl / 11 h / 80 °C 4: 89 percent / pyridinium hydrobromide perbromide / CHCl3 / 1 h / 15 - 30 °C View Scheme
参考文献
Tsunoda, Takashi; Tanaka, Akihiro; Mase, Toshiyasu; Sakamoto, Shuichi
Heterocycles, 2004 , vol. 63, # 5 p. 1113 - 1122
反应条件
1: 97 percent / acetic acid; cc. HCl / 11 h / 80 °C 2: 89 percent / pyridinium hydrobromide perbromide / CHCl3 / 1 h / 15 - 30 °C View Scheme
参考文献
Tsunoda, Takashi; Tanaka, Akihiro; Mase, Toshiyasu; Sakamoto, Shuichi
Heterocycles, 2004 , vol. 63, # 5 p. 1113 - 1122
反应条件
1: 100 percent / pyridine / 25 °C 2: 98 percent / potassium carbonate; potassium iodide / butan-2-one / 12 h / Heating 3: 93 percent / potassium t-butoxide / dimethylformamide / 2 h / 0 - 5 °C 4: 97 percent / acetic acid; cc. HCl / 11 h / 80 °C 5: 89 percent / pyridinium hydrobromide perbromide / CHCl3 / 1 h / 15 - 30 °C View Scheme
参考文献
Tsunoda, Takashi; Tanaka, Akihiro; Mase, Toshiyasu; Sakamoto, Shuichi
Heterocycles, 2004 , vol. 63, # 5 p. 1113 - 1122
反应条件
1: 100 percent / pyridine / 25 °C 2: 98 percent / potassium carbonate; potassium iodide / butan-2-one / 12 h / Heating 3: 93 percent / potassium t-butoxide / dimethylformamide / 2 h / 0 - 5 °C 4: 97 percent / acetic acid; cc. HCl / 11 h / 80 °C 5: 89 percent / pyridinium hydrobromide perbromide / CHCl3 / 1 h / 15 - 30 °C View Scheme
参考文献
Tsunoda, Takashi; Tanaka, Akihiro; Mase, Toshiyasu; Sakamoto, Shuichi
Heterocycles, 2004 , vol. 63, # 5 p. 1113 - 1122
反应条件
1: 93 percent / potassium t-butoxide / dimethylformamide / 2 h / 0 - 5 °C 2: 97 percent / acetic acid; cc. HCl / 11 h / 80 °C 3: 89 percent / pyridinium hydrobromide perbromide / CHCl3 / 1 h / 15 - 30 °C View Scheme
参考文献
Tsunoda, Takashi; Tanaka, Akihiro; Mase, Toshiyasu; Sakamoto, Shuichi
Heterocycles, 2004 , vol. 63, # 5 p. 1113 - 1122
反应条件
1: 28 percent / potassium carbonate / CHCl3 / 96 h / Heating 2: 61 percent / cc. sulfuric acid / acetic acid / 51 h / 70 °C View Scheme
参考文献
Tsunoda, Takashi; Tanaka, Akihiro; Mase, Toshiyasu; Sakamoto, Shuichi
Heterocycles, 2004 , vol. 63, # 5 p. 1113 - 1122
反应条件
potassium carbonate in chloroform
96 h; Heating;
参考文献
Tsunoda, Takashi; Tanaka, Akihiro; Mase, Toshiyasu; Sakamoto, Shuichi
Heterocycles, 2004 , vol. 63, # 5 p. 1113 - 1122
