2-巯基-5-甲基-1,3,4-噻二唑合成路线 （共 30 条）
反应条件
1: carbon disulfide; thiosemicarbazide With sodium carbonate in ethanol T=20 - 30°C; 4.5 h; 2: acetic anhydride With sulfuric acid in ethanol T=0 - 20°C; 2 h; Reflux;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 13 p. 3723 - 3727
反应条件
potassium hydroxide; hydrogen bromide; copper; thiourea; sodium nitrite in ethanol
反应条件
sulfuric acid T=5°C;
参考文献
Journal of Heterocyclic Chemistry, , vol. 47, # 4 p. 838 - 845
反应条件
hydrazine in dichloromethane 0.25 h; Ambient temperaturefurther reagents;
参考文献
Maiti, Samarendra N.; Spevak, Paul; Singh, Maya Prakash; Micetich, Ronald G.; Reddy, A. V. Narender
Synthetic Communications, 1988 , vol. 18, # 6 p. 575 - 582
反应条件
in argon matrix T=-263.16°C; 2.25 h; UV-irradiation;
参考文献
Journal of Physical Organic Chemistry, , vol. 23, # 1 p. 56 - 66
反应条件
hydrazine 1) DMF, 0-5 deg C; 2) DMF, 0-5 deg C; 3) DMF, microwave irradiation, 1 min; Yield given. Multistep reaction;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 37, # 5 p. 427 - 428
反应条件
phosphate buffer T=40°C; 0.0833333 h; Rate constant;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 3 p. 599 - 601
反应条件
phosphate buffer T=40°C; 0.0833333 h; Mechanism;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 3 p. 599 - 601
反应条件
in argon matrix T=-263.16°C; 2.25 h; UV-irradiation;
参考文献
Rostkowska, Hanna; Lapinski, Leszek; Nowak, Maciej J.
Journal of Physical Organic Chemistry, 2010 , vol. 23, # 1 p. 56 - 66
反应条件
pyridine; methanol 1.) CH2Cl2, 2.) from 0 to 5 deg C, 15 min; Yield given. Multistep reaction;
参考文献
Walker, Donald G.; Brodfuehrer, Paul R.; Brundidge, Steven P.; Shih, Kun Mao; Sapino, Chester
Journal of Organic Chemistry, 1988 , vol. 53, # 5 p. 983 - 991
