4-(1H-咪唑-4-基)苯胺盐酸盐合成路线 (共 9 条)
反应条件
hydrogenchloride; tin(ll) chloride T=80°C;
参考文献
Journal of the Chemical Society, , vol. 127, p. 2710
反应条件
1: potassium carbonate / ethylene glycol dimethyl ether; ethanol / 2 h / Reflux 2: palladium 10 on activated carbon; hydrogen / methanol / 24 h / 20 °C / 3750.38 Torr View Scheme
参考文献
Archiv der Pharmazie, , vol. 344, # 12 p. 775 - 785
反应条件
1: toluene / 24 h / Reflux 2: potassium carbonate / ethylene glycol dimethyl ether; ethanol / 2 h / Reflux 3: palladium 10 on activated carbon; hydrogen / methanol / 24 h / 20 °C / 3750.38 Torr View Scheme
参考文献
Archiv der Pharmazie, , vol. 344, # 12 p. 775 - 785
反应条件
ammonia; water; anhydrous copper acetate
参考文献
Chemische Berichte, , vol. 68, p. 1953,1956
反应条件
in ethanol; dichloromethane
8 h; Ambient temperature;
参考文献
Donetti; Cereda; Bellora; Gallazzi; Bazzano; Vanoni; Del Soldato; Micheletti; Pagani; Giachetti
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 380 - 386
反应条件
1: 88 percent / ethanol / Ambient temperature
2: H2O
View Scheme
参考文献
Donetti; Cereda; Bellora; Gallazzi; Bazzano; Vanoni; Del Soldato; Micheletti; Pagani; Giachetti
Journal of Medicinal Chemistry, 1984 , vol. 27, # 3 p. 380 - 386
参考文献
Bazzano; Vavoni; Mondoni; et al.
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 1 p. 27 - 33
反应条件
1: 85 percent / 4 h / Heating
2: 66 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
View Scheme
参考文献
Bazzano; Vavoni; Mondoni; et al.
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 1 p. 27 - 33
反应条件
1: 85 percent / 4 h / Heating
2: 66 percent / LiAlH4 / tetrahydrofuran / 4 h / Heating
3: 62 percent / ethanol / Ambient temperature
View Scheme
参考文献
Bazzano; Vavoni; Mondoni; et al.
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 1 p. 27 - 33