1,2,3,4-四氢-2-萘胺合成路线 （共 39 条）
反应条件
4-methoxy-N-(1-(naphthalen-2-yl)ethylidene)aniline; ammonium formate in methanol T=80°C; 8 h; Inert atmosphere; chemoselective reaction;
参考文献
Talwar, Dinesh; Salguero, Noemi Poyatos; Robertson, Craig M.; Xiao, Jianliang
Chemistry - A European Journal, 2014 , vol. 20, # 1 p. 245 - 252
参考文献
Chemische Berichte, , vol. 23, p. 885
Organic Synthesis Coll.Vol. 1 <New York 1932> S.486
Chemische Berichte, , vol. 21, p. 850,859
反应条件
3-cyanobenzylnitrile; 1,2,4-(Ph)3-3,5,6-(H)3-benzene; ammonia in water; acetonitrile T=20°C; Irradiation;
参考文献
Yasuda, Masahide; Kojima, Ryuji; Tsutsui, Hiroshi; Utsunomiya, Daigo; Ishii, Kazuaki; Jinnouchi, Koutaro; Shiragami, Tsutomu
Journal of Organic Chemistry, 2003 , vol. 68, # 20 p. 7618 - 7624
反应条件
1: With trifluoroacetic acid in dichloromethane T=0°C; 0.5 h; 2: Alkaline conditions;
参考文献
Barlow, James W.; Walsh, John J.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 1 p. 25 - 37
反应条件
hydrogen; palladium on activated charcoal in isopropyl alcohol P=2585.74 Torr;
参考文献
Bucholtz, Ehren C.; Brown, Randal L.; Tropsha, Alexander; Booth, Raymond G.; Wyrick, Steven D.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 16 p. 3041 - 3054
反应条件
1: With hydrogen; [Ru(η4-COD)(η3-methylallyl)2]; tetrafluoroboric acid; (S,S)-Et-DuPHOS in methanol T=50°C; P=75006 Torr; 20 h; 2: With trifluoroacetic acid in dichloromethane T=25°C; 1.5 h;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 6 p. 863 - 867
反应条件
hydrogen; nickel in methanol P=37503 Torr; Ambient temperature; Yield given;
参考文献
Tetrahedron Letters, , vol. 32, # 42 p. 5927 - 5930
反应条件
1: 100 percent / pyridine / 336 h / 4 °C 2: 94 percent / aq. sodium azide / dimethylformamide / 4 h / 45 - 50 °C 3: 5.1 percent / H2 / 5 percent Pd/C / propan-2-ol / 2585.74 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 16 p. 3041 - 3054
反应条件
1: 94 percent / aq. sodium azide / dimethylformamide / 4 h / 45 - 50 °C 2: 5.1 percent / H2 / 5 percent Pd/C / propan-2-ol / 2585.74 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 16 p. 3041 - 3054
反应条件
1: H2 / Pd/C / methanol / Ambient temperature 2: H2 / Raney nickel / methanol / 37503 Torr / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 42 p. 5927 - 5930
