1,2,3,4-四氢-2-萘胺合成路线 (共 39 条)
参考文献
Cymerman Craig et al.
Australian Journal of Chemistry, 1959 , vol. 12, p. 447,450,451
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Marini-Bettolo et al.
Gazzetta Chimica Italiana, 1950 , vol. 80, p. 281,292,296
反应条件
(i) Et3N, dioxane, (ii) LiAlH4, Et2O; Multistep reaction;
参考文献
Pitha,J. et al.
Collection of Czechoslovak Chemical Communications, 1960 , vol. 25, p. 2733 - 2745
参考文献
Bamberger; Kitschelt
Chemische Berichte, 1890 , vol. 23, p. 885
参考文献
Straus; Lemmel
Chemische Berichte, 1921 , vol. 54, p. 34
反应条件
sodium tetrahydroborate 1.) benzene, RT, 45 min, 2.) benzene, reflux, 5.5 h; Multistep reaction;
参考文献
Cannon, Joseph G.; Perez, Julio A.; Pease, Jonathan P; Long, John Paul; Flynn, Jan R.; et al.
Journal of Medicinal Chemistry, 1980 , vol. 23, # 7 p. 745 - 749
参考文献
Bamberger; Mueller
Chemische Berichte, 1888 , vol. 21, p. 1116
参考文献
Bamberger; Kitschelt
Chemische Berichte, 1890 , vol. 23, p. 885
参考文献
Chiavarelli; Settimj
Rend.Ist.super.Sanita, 1959 , vol. 22, p. 508,510
反应条件
supported Candida antartica lipase B in tert-butyl methyl ether T=38 - 40°C; 20 h; Molecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Poulhes, Florent; Vanthuyne, Nicolas; Bertrand, Michele P.; Gastaldi, Stephane; Gil, Gerard
Journal of Organic Chemistry, 2011 , vol. 76, # 17 p. 7281 - 7286
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 144 h; Resolution of racemateEnzymatic reaction; enantioselective reaction;
参考文献
Queyroy, Severine; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1759 - 1764